EFR 764: How to Build a Superhuman Gut with Dr. Jonathan Scheiman and Carolina Barsa

0:01:06 - Speaker 1 That's all good. Okay, I'll say it Cool Carolina. Jonathan, welcome to EverFord Radio. Thank you so much for being here. Yeah, I have explored the concepts of a lot about what you all do and it never ceases to amaze me, you know, in just my personal exploration, but also a guest on the show. We're talking about gut health, we're talking about chronic illness, talking about sleep All things that I think are all top of mind for everyone these days, regardless of what your health and fitness goal is. But before I jump into that, I want to keep it on brand four. We're here at Strong New York 2023. I'm curious what are you all's definitions of strength?

0:01:45 - Speaker 2 That's a good one.

0:01:46 - Speaker 3 You want to set it off.

0:01:49 - Speaker 2 I think you should leave this one. I have a thought, but here please do it Well.

0:01:53 - Speaker 3 I mean, new York is a good definition of strength. But perseverance, resiliency, entrepreneurship, creation, bringing things into the world and making sure you want to develop things that could help broader populations in the community I like it. I like it. We're New York based.

0:02:10 - Speaker 1 I want to make sure to plug that we're from New York.

0:02:13 - Speaker 2 New York is in the house Exactly New.

0:02:15 - Speaker 3 York's strong, yeah, I think that's very true.

0:02:18 - Speaker 2 For us, strength is about being able to persevere through everything and anything, and that includes mental, physical. All of that and I think what we're building is really trying to create education and awareness on how your health has a really strong impact on mental and physical strength, and so it's really exciting to be here and just see everyone really participating in this idea of strength.

0:02:44 - Speaker 1 What you just said kind of reminded me of, I think, something that I wasn't fully aware of education is strength. The more educated we become, the stronger we become, because we know what's BS when we look at it, we know when we're BSing ourselves. You know education is strength, and the more educated we can get whatever that looks like listening to this podcast, going to college, going to a course, reading, whatever, like you are strengthening your capabilities as a human being and community.

0:03:15 - Speaker 3 Oh, absolutely.

0:03:15 - Speaker 2 Community is huge for that.

0:03:16 - Speaker 3 Amen, I got to give a shout to my parents, public educators, my brother public high school teacher oh wow, we'll get into this. But even our roots like we spun out of Harvard University. So a lot of technology aren't there? No, not, at least. Well, we're New Yorkers, we don't care about Boston. But, that notion of creating something through knowledge but now making it accessible to everyone so they could, you know, utilize that for you know, their health and longevity journeys.

0:03:42 - Speaker 1 And you know, I'm so glad you kind of brought that up, because I feel like right now as we're recording 2023, there are so many different ways that someone can educate themselves, especially when it comes to physical and mental resilience, their health and wellness. But there's also a lot of misinformation out there. And when it comes to what we eat, what we ingest, what we supplement with you can really improve your situation, or perhaps really, you know, give yourself more work. We'll say. So how are you all different? What is the mission, what is the focus and how, through education, are you really changing the microbiome landscape?

0:04:23 - Speaker 3 we'll say I mean, everything is full stack and you know Carolina says this all the time. You know, there's a lot of companies out there that are based on formulation and taking things that already exist and repackaging them and marketing them. Proprietary blend, exactly. We're an innovation company, so we're developing new to the world microbes and probiotics that have novel functions that could help people in different ways, right, also, so, for instance, you know, we talk about the microbiome and the notion of probiotics typically is like oh, digestion and stuff like that, but we have probiotics that help us with sleep health through, like the gut brain access. We have probiotics that eat lactic acid to fight fatigue and promote endurance. Wow, so now you're talking about gut muscle access. So all of this is through like technology and bioscience and really bringing innovation to the world, right, and that's how we're truly differentiated.

0:05:09 - Speaker 2 Yeah, and I'd say, you know, when you think about the supplement industry, I think 12% of supplements in the industry are certified by a third party to make sure that they contain what they say they contain.

0:05:18 - Speaker 1 And they don't. 12%, that's like nothing.

0:05:21 - Speaker 2 Yeah, and you know, we do very rigorous testing on all of our products. So we're innovation based, but we also are making sure that we're driving efficacy in the benefits that our products deliver. So clinically validating finished products, not just making claims based on some of the ingredients.

We have and then we're testing to make sure that our products are clean and delivering exactly what it says. So NSF informs, for these are organizations that really are checking for banned substances and making sure that your products contain exactly what is in the label. So I think that's really important to note. You know, it's about delivering safe and efficacious solutions that are not just marketing and not just a lot of fluff that people can't.

It's hard. I mean even us being educated and knowing the industry. Sometimes it's easy to see something that's very well marketed and be like this is promising.

0:06:10 - Speaker 1 Yeah, Damn it, your marketing got me. Yeah, you know what you were kind of describing before we hit record is really, for me at least, novel. But before I get there, I want to kind of hit where you just said, jonathan, about gut health for things other than traditional gut health goals. I think, at least when I used to hear, oh, gut health, I got to do a cleanse, I got to do a gut reset, I got to focus on fiber probiotics, probiotics just for the sake of the gut. But I'm hearing you say that no, we're using gut health to focus on every other thing.

0:06:43 - Speaker 3 Yeah, so again, just how you started. This is so amazing, like strength and community and diversity. So, first and foremost, just I think most people noticed by now we have trillions of microorganisms in and on our body. We're as much bacteria as we are human. We have 100 times more bacterial genes in our body than human genes. Yeah, so this microbial ecosystem pretty much impacts everything we do from a functionality, longevity, performance and health standpoint. But to take it a step further, just about knowledge and discovery, most probiotics are decades old. They come from food, baby poop, the environment, animals, baby poop. Yes, see the things you know and the things you didn't know, but these are antiquated solutions.

Think about what we're doing, and I mentioned this. Fitbiomix is a microbiome company, and what we do is we decode the biology of the most fit people in the world to understand what's unique in their physiology that drives health.

0:07:44 - Speaker 1 That's what I was handing out earlier for the listener, just so we can connect all the dots.

0:07:48 - Speaker 3 But then we translate those insights into next generation health and longevity solutions, so even the concept of knowledge and applying it towards decoding very unique biological states, so we could learn what drives health and now apply that to help everyone. That's what FitBioMix is doing.

0:08:05 - Speaker 1 OK. So I have a little devil's advocate question to that. So let's say I'm gonna loosely break down the silence here. You're taking the gut health, the microbiome of super elite, high-performance people that are in very good-standing health, and then and then creating a product to then provide to people that don't have that. Why wouldn't we then, why wouldn't we instead adopt how they got to that place first, instead of taking another pill?

0:08:36 - Speaker 3 I mean it's hard, it's hard right.

0:08:39 - Speaker 1 Are you finding it's more these people like naturally, just like it's a genetic situation, or you finding like, oh no, through these protocols I achieved this kind of unique homeosynthesis?

0:08:49 - Speaker 3 So for instance, just so you know, actually a majority of microbiome Composition is not genetics-based. It's a lot of diet, it's a lot of environmental exposure, antibiotics, exercise, biography, anything you could think of pretty much not genomics-based. But then you talk about why can't we do that? I think Not everyone has access to. You know personal nutrition nutritionists.

0:09:16 - Speaker 1 No one, not everyone has.

0:09:18 - Speaker 3 You know the means to sort of eat like an elite professional athlete not everyone. For instance, our second product is arrived from ultra marathon runners that run a hundred miles at a time right. Not it's kind of basically decoding what the result is of that that drives optimal health and performance, and making that accessible to everyone. I like because because we next gen. Health is a right. Everyone deserves to have access to that.

0:09:43 - Speaker 2 So, yeah, I think another important point is, you know this idea of accessible. So not everyone can have the education or the means to eat the right way or exercise or have the time right, if you're a Single mother and you're trying to juggle work and take care of your kids, or even if you're married, whatever. Like the idea of the reality of oh, just work hard and you can achieve it is not reality for everybody.

I think, understanding the reality of what people are working with and how you can help, provide them or aid them in being able to achieve those goals. The other challenges the reality of our food supply, or food supply, is not the way it was 10 years ago, 20 years ago. We have a lot more toxins, a lot more pesticides, a lot less nutrients, so the vitamins and minerals that your body is taking in Food are not the same level because getting access can be one solution for the access to more or to less nutrient dense food.

It's like we just kind of cut off one arm to say barely save the other, you know, and the reality is, a lot of people are eating processed foods because of time or cost, and that creates more opportunities for toxins to get into your bloodstream, so you have Leaky gut and a lot of these autoimmune conditions that are coming up because of the reality of our food supply, and so Eating healthier is not necessarily gonna be the only solution that's gonna help get you to that point where you can actually be armed to support yourself.

So that's where I think some communication is important, but it's not a magic pill. And Activity diet all these things are factors, so it is a balance of nature and nurture. But how do we help people achieve those goals in a more efficient way?

0:11:15 - Speaker 1 Would you all say that Optimizing gut health as much as one can before supplementation is achievable only through diet, as in what we're eating or not eating, what other factors can you unpack for us that might be contributing to less than ideal that help?

0:11:33 - Speaker 2 Yeah, exercise activity. So Lack of activity actually impacts your gut microbes. Things like stress, smoking, alcohol all these factors will change the composition and the Diversity of floor and your gut and those all connect to your overall health. So even thinking about the gut is the second brain. Oftentimes we really see that the gut has a big impact on it's very bi-directional. So it has impact on your physical well-being but also mental well-being and then your mental well-being your physical aspects also impact your gut health.

0:12:04 - Speaker 3 I also just wanted to say a couple of things going back to your question and optimization. But why? Maybe diet doesn't necessarily work, I think traditional medicine or biomedicine. A lot of times we look at disease or sort of like what's broken and how do we correct it to promote health. But I think we're taking a fundamental to the different approach. We're looking what does work, what's naturally selected, natural evolution, that's driving health in super performers and then sort of learning from that to help everyone. To your point, even coming out of the pandemic. If you look at sleep, 100 million Americans suffer from insomnia. It's the number two 100 million. One in three Americans suffer from insomnia.

0:12:48 - Speaker 1 I had no idea it was that heavy of a statistic it's the number two health concern amongst consumers.

0:12:53 - Speaker 3 Then you think about how are we trying to solve that? Okay, is it like we're taking melatonin, which may be doing more harm than not? Think about the notion. Sleep is the number one performance-enhancing drug.

0:13:07 - Speaker 1 Amen to that.

0:13:08 - Speaker 3 Think about a step further decoding the microbiome of performers with optimized sleep patterns and identifying probiotics that can help everyone with their sleep. That's where we're going with this.

0:13:20 - Speaker 1 Okay, so then I feel like we're really getting into the products here. Walk us through. What do you all do? How is this different and what unique problems are you solving?

0:13:31 - Speaker 3 You want to take this, Go for it. Okay, yeah, I mean listen. I think our mission is to fundamentally change the way we understand and optimize our bodies, full stop. We're basically looking at the microbiomes of super fit phenotypes and then translating them to probiotics. Some of the conditions we're going after gut health, sleep, fatigue, strength, women's health, recovery, mood. We're building out programs for all these different functional applications. We've already solved sleep health and fatigue and those are our first two products. For instance, our first product, Nella, is a daily product capsule you take once a day and it helps with improved quality of sleep, fewer sleep disruptions, and it helps with your digestive Very natural microbiome intervention, if you will.

0:14:23 - Speaker 1 I love, if I could just pause you right there. I love this approach because what it's also doing for the aware consumer is connecting the dots of. I think I have one problem, or there's one area of my health that I wish was better, and I'm focusing only on it, but actually it's most likely rooted in something else, and I think that is where we maybe shoot ourselves in the foot by trying to do the right thing of addressing and solving one problem, but missing the mark of our body is a system of other systems, and so I think that's huge, and I think it's a big takeaway to the listener how they pick up on and I'll just say to your point system and systems.

0:15:07 - Speaker 3 we start by saying trillions of microorganisms in our gut and that's like the ultimate system in our body that we need to pay attention to.

0:15:15 - Speaker 2 I think the biggest thing is we can't keep masking something, and that's what, as a culture, we have been trained to do. You have a headache? Pop some Tylenol. Don't worry about whether it's because of inflammation or because of lack of sleep. What is your headache really caused from and addressed?

0:15:27 - Speaker 1 by.

0:15:28 - Speaker 2 It's pop some Tylenol or et cetera and call it a day. And so I think the idea of masking something versus addressing a root cause is really a mind shift that we need to get into.

0:15:37 - Speaker 1 And I forget what you said earlier, Jonathan, the prompt to this. But think about how much happier we could be when we improve our gut health. Specifically, last I checked, the stat seems to be getting a little bit higher and higher 67, if not 70% of our oxytocin or serotonin excuse me 90%.

0:15:55 - Speaker 2 90% of serotonin comes from the gut, I can't keep up 100% of immunity.

0:15:59 - Speaker 3 It's made in our gut.

0:16:01 - Speaker 1 So imagine so you're literally unhappy with your life. You're unhappy maybe inexplicably. Of course, that could be a lot of different other reasons, but focusing on our gut, health, allowing our body to really get to a place where it can create the molecule, the thing that we need to feel happy, you might think it's like, oh, my partner, my life, my job, my this, it could just be your gut, could be all those things it could be yeah it could be.

0:16:27 - Speaker 2 It could be. I think. The research continues to prove that gut-bring connection. It continues to see more and more evidence around specific microbes, corollates and things like depressions, schizophrenia, add, even Alzheimer's, parkinson's so many neurological diseases that are connected to the gut, and nerves.

0:16:44 - Speaker 1 We just learned here from Lisa and Nicola earlier on the stage.

0:16:47 - Speaker 2 Yeah, yeah, it's very true.

0:16:50 - Speaker 3 Yeah, I think, again tying back to environment, nature versus nurture. If you look at our dietary habits high salt, high fat, high sugar it's depleting our microbial ecosystem. Think about antibiotics pre-usage. We're not sleeping well, we have high stress, we're coming out of a pandemic. So, you know, Carolina has an amazing way of looking at this. It's really looking at folks and phenotypes that thrive in modern society, People that have been able to be resilient to those symptoms and still perform at an elite level. I just want to say it's not about athletes. You know, athletes, believe it or not, are as rare as centenarians, Elite athletes. They both represent the 0.01% of the human population.

0:17:32 - Speaker 1 But yet stand out the most because of what they can accomplish Exactly.

0:17:35 - Speaker 3 So they have these very unique attributes in terms of endurance, strength, mental toughness, recovery. But for us think about that, that's just neurology immunology metabolism.

0:17:46 - Speaker 1 We can break all that down and understand it.

0:17:48 - Speaker 3 Exactly.

0:17:48 - Speaker 1 Well, we can run a test for it Exactly.

0:17:50 - Speaker 3 So we could see what's working in people that are resilient to the issues with modern society. And now some apply those learnings to help people confront modern society. Right, Right, so full circle.

0:18:02 - Speaker 1 Yeah, what's besides symptoms that we've maybe been talking about, what would be one or a couple maybe recommended testing protocols that someone could explore? For hey, I think I got some gut health issues going on, but I'd like to really make sure. What can they do to really get a lab analysis for that?

0:18:23 - Speaker 3 There's plenty of microbiome sequencing companies out there, kind of like the 23 Meese, except for like microbiomes and stool and stuff like that. But I think these symptoms are fairly, for instance, constipation. Maybe you don't have regular bowel movements. Again, I think if you're not able to sleep during the night right, I mean, these things are you don't really need a test, right? That's true.

0:18:47 - Speaker 1 You just need a hard look in the mirror, maybe Exactly. Or a look in the toilet or a look at your poop and pee. Probably a look in the toilet. Yeah, it's very indicative.

0:18:55 - Speaker 2 We can look at the Bristol School of Model and pee.

0:18:56 - Speaker 1 Let's go there. Let's go there, break it down. I want to look at my poop. I want to figure out from that fecal sample what is going on in my gut. What should I be looking for as a red light, yellow light, green light?

0:19:12 - Speaker 2 I think one is frequency. How often are you going to the bathroom? So I definitely think frequency is a big aspect. If you're, ideally you should be going at least once a day, depending on how active you are and what you're eating, how much fiber you're taking, et cetera. But if you're going once a week you have a problem. If you're going every three days, you probably have a problem. Every other day maybe you're OK, but really every day would be ideal.

0:19:37 - Speaker 3 Also I'd say just formation, how smooth it is, Obviously, if it's not to take it there, but super watery and diarrhea.

0:19:46 - Speaker 1 This is a safe space. Yeah, I read you.

0:19:48 - Speaker 3 We're here to learn, but on the flip side right if you're on the toilet, it takes you 20 minutes to get something out right and you're constipated, and so a nice log, a smooth log, is probably what you would want to aim for right, I had to guess on the show. Shadow of the Novel Party.

0:20:02 - Speaker 1 I think she told me, from your wrist to your elbow crease ideally. It is the ideal length of an elimination. It's like a healthy log. I was like Mary, you're killing me. I feel like I'm a pretty regular guy, but I'm not a regular guy.

0:20:17 - Speaker 3 That's a big thing right, you got to get some more probiotics. Man, the human body is truly remarkable what you store in there and what it produces.

0:20:26 - Speaker 1 Who was it? Was it John Wayne, I think? I don't know if this is true or not, but the story is, when he died and they're doing the autopsy or something, he had something I think like 15, 20 pounds or something crazy of just stored fecal matter gut crap up in there. It was the Wild West. He was just eating a cow a day, probably at that point but I do enjoy my steak.

But we've come a long way in terms of understanding the human body. We've come a long way in terms of what we can test for and even just bringing education to the public and a health promotion aspect of hey, if you're feeling like this, looking like this, not feeling like this, not looking like that, here are some things that you might want to be looking out for. What do you think right now is one of, or a couple of, the biggest pieces of misinformation when it comes to that health?

0:21:20 - Speaker 2 I think one big thing is that people think you only need a probiotic if you've taken antibiotics or if you have IBS, and that's not necessarily the truth. I think there are people who the probiotic might do more damage, but for a lot of people, a high quality probiotic actually does a lot of holistic good and preventative and holistic health. I think the other big myth is the idea that all probiotics are the same, because they're not, and I think people have tried probiotics and like, well, I've tried and they don't work. And I'm a culprit. I'm in my mid 40s. I had my first colonoscopy in my early 20s. I have IBS in my whole life.

I've tried so many probiotics and nothing worked. And for me and Nella, I mean when we first did our open label study before we were even, we just got our first samples in these little Mylar patches and I was like I'm going to just start trying them- Game changer. I mean, I won't talk about poop all day, but like game changer, because especially for women it's a big deal. Women 75% of women will experience some kind of GI symptoms at least a few times a month.

That's not saying that's how many people have IBS or digestive issues, but they will experience the symptoms and they're connected to a lot of factors and women's health can be a whole other topic we can dive into and spend an hour podcast on alone.

0:22:30 - Speaker 1 Oh, when my wife tells me she's like I pooped today, I'm like oh, thank God, I'm so glad to hear that. When I don't hear that for a couple of days, I'm like what's going on? What's going on, yeah.

0:22:40 - Speaker 2 But I mean, I think the biggest thing is just they try probiotics, they think it doesn't work and so they become skeptical, which I understand because I was the same way. So I do think that's the biggest thing Having a really good quality probiotic that you know has been clinically validated, where testing has been done. Like for us, we have a money back guarantee. You don't love it, we'll give you money back, because if it doesn't work for you, then we don't want you to be.

That's amazing, the price for right and we see amazing retention. I mean we have customers that have been on a subscription for 16-18-19 months. So I think there's a lot of misconceptions around, like Probiotics are just if you have IBS or if you take antibiotics, and they're only if you.

You know they're all the same and those are some of the big areas and we're starting to see more evidence and research papers come out talking about the Got muscle connection, got brain connection, mood, physical activity performance. I think there's some of those myths are definitely Making their way. There's more education.

0:23:36 - Speaker 1 I agree, I agree, yeah, but also it's very important, be a study of one. N equals one, you know, do your homework, do do diligence, but also pay attention to what your body is telling you about a certain situation. Like a lab can tell you one thing, but I'm here to tell you this is health coach chase, coming on Like your body is going to tell you what it needs, whether once. Yeah, pay attention to those labs and more quantitative markers, for sure, but it can say one thing and you can feel a totally other.

0:24:06 - Speaker 3 Yeah, I mean the other thing to not necessarily probiotics. This is maybe a tangent, but you know 60% of all US adults have at least one chronic disease right.

0:24:16 - Speaker 1 60% of American adults have at least one chronic disease.

0:24:20 - Speaker 3 It's the number one leading cause of death in the US. It costs this country up to four trillion dollars in health care costs Wow, right. So think about what we're doing in terms of like biotech, and you know we're talking about a ten-year billion dollar journey to develop a drug to treat disease. But I think you know this notion of health and health care. Maybe there's a misconception there, right, we shouldn't necessarily want to treat diseases, we should try to prevent them. Right, and I think that ties into our gut microbiomes and probiotics, right? So, as Karen Lee has said, it's not just about Okay, I'm traveling and I have diarrhea, I have IBS. It's actually a form of preventative medicine.

Yeah, right helping you with your sleep, helping you with your fatigue right, helping you with your strength. Probiotics are about holistic health, and that's what we're trying to promote with FitBioNics.

0:25:06 - Speaker 1 Amazing. Well, the last question I ask everybody Is to like bring it all together and bring it home to the theme of the show, and that's how can we take this information, how can we apply it into our lives so that we can move forward, live a life ever forward? What does that mean to you all? How do you live a life ever forward? Do you hear those two words? Yeah, I think.

0:25:27 - Speaker 2 I think it's such a holistic and unique thing for everybody. So I, you know, it comes back to a lot of our values as well and this idea of being surrounded by people who support you and your journey, people who teach you and help you be a better person, whether it's, you know, opening your eyes to opportunities for you to be better, educating you on certain topics, or just Supporting you on your journey, whether you're in your ups or your downs, and I think those are really key aspects.

I, I think our physical health has such a huge impact on our mental health and right now we just see such a huge increase in even younger kids experiencing a lot of depression and Really anxiety challenge with life and it's coming out of post pandemic issues.

0:26:11 - Speaker 1 I think we're we're only tapping into, unfortunately, the amount of health problems, especially mental health, that I can be, you know, years down cover.

0:26:19 - Speaker 2 And I think that's where just the idea of being kind and paying it forward and helping people without expecting something in return Is very important for me personally. So this idea of constantly giving back and thinking about how do we help support the whole so we're all Really collectively. Yeah progressing and moving forward.

0:26:36 - Speaker 1 I'm with you. I want you, jonathan.

0:26:39 - Speaker 3 Yeah, I agree, like I, growing up I was a ball player, I played at st John's and you know basketball communities phrase like each one teach one right. And this is it again each one teach one. I like that. And you know just my story again, I got my pm Say from NYU. I got, I did my postdoc at Harvard and everyone told me like you have to start a biotech company and either Boston or the Bay Area is like no Right. Like for me, it's one of my goals to make New York the leaders in next-gen health right and it's about building a community here.

0:27:11 - Speaker 1 New York doesn't need any help getting put on the map, but I like. I like the different angle. I respect that. Yeah, absolutely.

0:27:17 - Speaker 2 I think that New York brings a level of diversity. Yeah, it's often not in bioscience medical field, whether it's looking and studying at different ethnic backgrounds and men and women. Women were not including clinical trials until 1993. Like that is just 93?. Yes, and most research, most protocols, like so much, is not based on the female phenotype. What a huge detriment to society, which is not okay, and that is not how women's body operates.

So you know, there's a lot that we can do by thinking about diversity, about whether it's through gender, through phenotypes, through ethnic backgrounds, and about lifestyles you know, the dietary lifestyles. All of these things are important. So for us, putting that into our science, both from a discovery but also an efficacy perspective, is very important, and so I think New York really is a place where we can really bring it all together and build that diversity.

0:28:07 - Speaker 1 I love it, amen, love it. Well, what's next on the horizon for you guys?

0:28:11 - Speaker 3 Well, besides taking over New York, Well, we want to change the world right. I mean, we already have a product on market that's helping thousands of people with their sleep health and their gut health. Next year, we're launching our second product, again a Next Gen Micro-T Lactic Acid and Compact Fatigue. Think about daily fatigue, chronic fatigue, and then we're building programs. We're not something that we're building programs for women's health, for strength, mood recovery, anything you could think of from sort of a health and longevity standpoint. We want to decode it and now recode that into Next Gen probiotics.

0:28:43 - Speaker 1 Okay, so I lied. I'm going to ask one more question here. You kind of just sparked a little interest in me, so by the time this goes live, I think I'll have done a little 2024 predictions episode. There are a few things on my radar that I really think are kind of novel and some that are finally getting the regular attention they deserve for the masses, and I think, inflammation.

I think, inflammation, the way that metabolic health has been trending for lack of a better term than the last year or so, at least in my world. I feel like inflammation. Getting key markers for inflammation like CRP, getting all the extensive metabolic panels, but also focusing qualitatively on inflammation in the body and the gamut of things that it can do for you. What's your take on that, Maybe through the lens of gut health and inflammation?

0:29:34 - Speaker 3 I mean Caroline already mentioned it the notion of leaky gut that could cause systemic inflammation. I think you actually had the right stat but the wrong physiological parameters. So actually 70% of the immune system interacts with our gut, excuse me, okay.

0:29:48 - Speaker 1 Okay, you had the right statistic.

0:29:50 - Speaker 3 Sometimes I don't work good, but we fundamentally believe again, gut immune access, inflammation this could all be modulated and corrected and prevented through probiotics and our gut microbiome. And, to your point, even this term not just inflammation, but inflammation and how inflammation is relative for longevity.

0:30:11 - Speaker 1 I'm cosigning on that, I'll give you credit. That's amazing Inflammaging.

0:30:16 - Speaker 3 Yeah, that's a term that's been in there. But you're right, I think next year it's going to become more and more household. It's not going to be niche, it's going to be like no, this is just how we think about health and longevity.

0:30:29 - Speaker 1 Well, also to kind of reverse engineer a little bit, I think right now there's a new breath of fresh air under centenarians and longevity. Dan Butler's work has recently been highlighted again on Netflix, thanks to people here like Dr Gabrielle Lyon, people like David Sinclair, the whole crew over at Dr Chris Rinsh at Amazenta's Timeline. Just looking at mitochondrial health, longevity the game, we're seeing a lot of things such as mitochondrial health focusing on that, but what really we're looking at is a reduction in inflammation. And when we look at the people that are still squatting, you know a body squat down and get up and you know 90, 95, 100 years old reduce inflammation. You know how do we unpack that.

0:31:08 - Speaker 3 Yeah, so.

0:31:09 - Speaker 1 I'll just, if I may three things quickly.

0:31:12 - Speaker 3 One everyone should Google Viennela, right, and you know elite athletes. But again, you mentioned mitochondria produces lactic acid as a result of strenuous exercise, right, it's sort of a marker fatigue. That lactate goes into the gut, where an organism Viennela could eat it up and convert it into anti-inflammatory metabolites. No way. Yeah so that's what's coming up next year with the Biomics. Awesome, Nella Wow.

0:31:36 - Speaker 2 And.

0:31:37 - Speaker 3 Nella has anti-inflammatory properties as well. But then even think I mentioned, you know, programs in strength and decoding strength phenotypes. Think about muscle health, but not just from like bench pressing. Think about it like sarcopenia and healthy aging. Right, yeah, so again, all these things are connected performance to health, to longevity.

0:31:55 - Speaker 1 So I think the you just said sarcopenia reminded me I recently had Dr Kelly Starrett and his wife Juliette on the show from the ready state and they had an amazing this new book out, this amazing research courted about. We're looking at longevity. Of course, there are a lot of biomarkers we can look at that help with that, but really the number one strength test is just like leg strength being able to stand up from a seated position unaided and what they do to measure that is look at, you know, leg strength, quadrille basically, and so think about how fundamental that is, something so easy someone can focus on that is going to reduce inflammation, like you said. Like if I could just focus on leg strength, I'm adding, maybe potentially years to my life.

0:32:37 - Speaker 3 By the way, I'm going to take it full circle. You start. What does strength mean to you? Longevity, right.

0:32:42 - Speaker 1 Exactly, exactly being as strong as possible for as long as possible. Amen.

0:32:48 - Speaker 2 You want to thrive in life, not survive. There we go. I love it.

0:32:50 - Speaker 1 Well, this has been great. Thank you guys so much for your time on the show Working my audience go to connect more with you guys, what you got going on which, by the way, I'm going to take this as a little sign from the universe my dog, which I see you get your pop here, by the way?

0:33:02 - Speaker 2 Yeah, I'm here.

0:33:03 - Speaker 1 She's been going through it with some, like I assume, gut issues like skin itchiness, rassiness. Her name is Nella. And so we are going through it with her diet and stuff right now, so I'm taking this as like all right, I see you. I see you.

0:33:16 - Speaker 3 The universe is rooting for you, yeah.

0:33:20 - Speaker 1 Where can we go? Is it just?

0:33:21 - Speaker 2 Yeah, so you can come to our website, wwwbiomixcom. You can also follow us on social media at biomix.

0:33:29 - Speaker 1 F-I-T-B-I-O-M-I-C-S. It's been a long day. It's been a long day.

0:33:37 - Speaker 2 So yeah, at biomixcom or.

0:33:42 - Speaker 1 We'll plug all the links. That's all for everybody. We got you, carolina, dr J, it's been great having you guys on the show. Thank you so much.

0:33:47 - Speaker 2 Awesome, and if people want, you can use the code STRONGNAYORK for 25% off on. Nella, so definitely check us out. Come to our website.

0:33:55 - Speaker 1 Yeah, we'll give you a link for you to I might need some for Nella. Actually, We'll give you some samples. Is this okay for pets?

0:34:02 - Speaker 2 Probably.

0:34:03 - Speaker 1 Unofficially. I mean I get my Nella for Nella Hashtag yeah, nella for Nella, nella for Nella. Look anything that'll help her out.

0:34:09 - Speaker 2 I buy a probiotic from my dog and it has these three streams in it.

0:34:12 - Speaker 1 Amazing. So, All right, all right, cool Cool, got health as a part. We'll take it. Thank you guys, so much Awesome.

0:34:19 - Speaker 2 Thank you.